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Rate of killing by moxifloxacin and gatifloxacin. Exponentially growing cultures of M. tuberculosis H37Rv were incubated for the indicated times with 20 times the MIC of gatifloxacin (open circles) or moxifloxacin (filled circles). Aliquots were then removed, diluted, and plated on drug-free 7H10 agar for determination of CFU. Data shown are averages, with error bars indicating ranges of values.
