TABLE 1.

Susceptibility of M. tuberculosis to quinolones

Compound	MIC (μg/ml)a	LD99 (μg/ml)a	LD99/MIC
Moxifloxacin	0.04	0.8	20
Bay y3114b	0.05	10c	200c
BMS-433368	0.05	1.5	30
Gatifloxacin	0.03	0.5	15
Ciprofloxacin	0.15	5	34

^aSimilar values were obtained in replicate experiments. Concentration increments were 20% for determination of MIC.

^bBay y3114 is a C-8-H cognate of moxifloxacin (Fig. 1).

^cLD₉₉ was determined by extrapolation.