TABLE 2.
Test performance of LCR for C. trachomatisa
| Test | Cultureb (n = 212)
|
TMAb (n = 217)
|
PCRb (n = 255)
|
PCRc (n = 255)
|
||||
|---|---|---|---|---|---|---|---|---|
| Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | |
| LCR-PreservCyt | 90 (79-97)d | 89.4 (84-94) | 92 (82-97) | 99.5 (91-98.2) | 96 (88-99) | 95 (91-97.8) | 93 (85-98) | 95.5 (92-98) |
| LCR-cervix | 96 (86-99.5) | 90 (84-94) | 100 (94-100) | 98 (94-99.6) | 100 (95-100) | 97 (93-98.8) | 99 (93-99.97) | 98 (94-99.4) |
| LCR-urine | 92 (80-98) | 91 (85-95) | 93 (83-98.0) | 97 (93-98.9) | 97 (90-99.6) | 97 (93-98.8) | 97 (90-99.7) | 99 (96-99.9) |
a
Performed on PreservCyt (LCR-PreservCyt), LCx transport media (LCR-cervix), and urine (LCR-urine) using culture (one specimen), TMA (one specimen), and PCR (one and three specimens) reference standards for detection of C. trachomatis.
b
Cervix.
c
Cervix, vagina, and urine.
d
Values in parentheses are 95% confidence intervals.