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. 2005 Apr 4;201(7):1125–1134. doi: 10.1084/jem.20041869

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Copyright © 2005, Government

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Figure 1. — LAT Y136F phenotype is dominant in HY⁺ LAT Y136F^m/m female and male mice. (a) Thymocytes and lymph node cells from HY⁺ LAT^+/+ and HY⁺ LAT Y136F^m/m female mice were analyzed by flow cytometry using anti-CD4, anti-CD8, and T3.70 antibodies. CD4 versus CD8 dot plots are shown either ungated or gated on T3.70^hi cells. HY⁺ LAT^+/+ and HY⁺LAT Y136F^m/m female mice were 41 and 8 wk of age, respectively. (b) Thymocytes and lymph node cells from HY⁺ LAT^+/+ and HY⁺ LAT Y136F^m/m male mice were analyzed as described in (a). HY⁺ LAT^+/+ and HY⁺ LAT Y136F^m/m male mice were 7 wk of age. (c) Thymocytes and lymph node cells from a LAT Y136F^m/m mouse (5 wk old) were analyzed as described in (a).