Table 2.
Feature type | percent identity | query features | homolog features | true positive | false positive | new features |
PFAM-A domain | <90% | 161 | 161 | 160 | 0 | 4 |
<50% | 161 | 150 | 149 | 0 | 3 | |
PROSITE pattern | <90% | 166 | 165 | 160 | 0 | 5 |
<50% | 166 | 153 | 148 | 0 | 4 | |
Uniprot site | <90% | 360 | 305 | 260 | 0 | 64 |
<50% | 360 | 288 | 235 | 0 | 56 | |
secondary structure | <90% | 1486 | 1265 | 1150 | 1 | 987 |
<50% | 1486 | 1197 | 1009 | 1 | 802 | |
Total | <90% | 2283 | 1896 | 1730 | 1 | 1060 |
<50% | 2283 | 1788 | 1541 | 1 | 865 |
Percent identity indicates the maximum similarity of the sequences in the alignment with the query. 'Query features' is the number of sequence features for the query available in the public databases. 'Homolog features' is the number of features found in the other sequences in the alignment that correspond to a feature in the query. True (or false) positives indicate the number of features propagated by MACSIMS that match (or mismatch) with known query features. 'New features' is the number of features predicted by MACSIMS that are not currently found in the public databases.