TABLE 3.
Comparison of the Merck Pn assay with the international Pn assaya
| PnPs Serotype | Prevaccination
|
Postvaccination
|
Fold rise
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| International assay
|
MRL
|
International assay
|
MRL
|
International assay
|
MRL
|
|||||||
| GMT | SD | GMT | SD | GMT | SD | GMT | SD | GMT | SD | GMT | SD | |
| 1 | 0.2 | 1.06 | 0.2 | 1.15 | 2.8 | 1.38 | 2.4 | 1.21 | 13.0 | 1.11 | 12.3 | 1.29 |
| 3 | 0.4 | 1.01 | 0.5 | 0.92 | 1.5 | 1.09 | 1.3 | 0.86 | 4.3 | 0.93 | 2.5 | 0.86 |
| 4 | 0.2 | 1.25 | 0.3 | 1.27 | 2.4 | 1.33 | 3.9 | 1.30 | 10.6 | 1.00 | 11.8 | 1.06 |
| 6B | 0.7 | 1.10 | 1.0 | 1.15 | 3.2 | 1.48 | 5.7 | 1.32 | 4.5 | 1.09 | 5.9 | 1.01 |
| 7F | 0.6 | 1.24 | 0.6 | 1.27 | 7.0 | 1.33 | 7.2 | 1.29 | 11.8 | 1.23 | 12.2 | 1.23 |
| 8 | 0.3 | 1.07 | 1.1 | 0.83 | 4.6 | 1.10 | 6.4 | 0.83 | 13.3 | 1.16 | 5.7 | 0.92 |
| 9V | 0.7 | 1.37 | 0.8 | 1.47 | 5.7 | 1.32 | 6.0 | 1.19 | 8.4 | 1.03 | 7.5 | 1.05 |
| 12F | 0.1 | 0.97 | 0.1 | 1.17 | 1.0 | 1.62 | 2.0 | 1.64 | 8.7 | 1.32 | 13.7 | 1.52 |
| 14 | 1.8 | 1.55 | 4.5 | 1.18 | 15.1 | 1.79 | 26.1 | 1.48 | 8.4 | 1.40 | 5.8 | 1.24 |
| 18C | 0.9 | 1.19 | 1.7 | 1.25 | 7.9 | 1.31 | 13.2 | 1.26 | 8.6 | 1.15 | 7.7 | 1.33 |
| 19F | 0.9 | 1.00 | 2.0 | 0.96 | 4.3 | 1.48 | 11.2 | 1.35 | 4.7 | 1.07 | 5.7 | 1.07 |
| 23F | 0.5 | 1.24 | 1.0 | 1.08 | 3.2 | 1.64 | 5.5 | 1.44 | 6.8 | 1.33 | 5.4 | 1.19 |
a
Pre- and postimmunization adult serum samples (n = 120) were quantitated for total IgG as described in Materials and Methods. MRL, Merck Research Laboratory Pn assay.