TABLE 1.
Genes with changed expression in the gcn5− mutant
Gene namea | Description of gene product | Mean fold change | P value | |||
---|---|---|---|---|---|---|
Reduced expression in gcn5− mutant | ||||||
SPAC1002.17c | Uracil phosphoribosyltransferase activity (predicted) | 0.295 | 0.0032 | |||
dfr1 | Dihydrofolate reductase | 0.385 | 0.0010 | |||
pex7 | Peroxisomal targeting signal receptor | 0.432 | 0.0005 | |||
SPAC5H10.03 | Phosphoglycerate mutase family | 0.435 | 0.0001 | |||
SPAC12G12.06c | RNA 3′-terminal phosphate cyclase (predicted) | 0.444 | 0.0124 | |||
SPBC839.18c | Oxidoreductase (predicted) | 0.466 | 0.0020 | |||
SPAC1039.02 | Calcineurin-like phosphoesterase (predicted) | 0.474 | 0.0005 | |||
SPBC1683.05 | Thiamine transporter (predicted) | 0.486 | 0.0151 | |||
obr1 | Ubiquitinated histone-like protein Uhp1 | 0.487 | 0.0003 | |||
Increased expression in gcn5− mutant | ||||||
mei2 | RNA-binding protein | 5.584 | 0.0055 | |||
ght5 | Hexose transporter | 4.686 | 0.0159 | |||
SPCC1739.08c | Short chain dehydrogenase | 4.605 | 0.0100 | |||
SPACUNK4.10 | 2-Hydroxyacid dehydrogenase (predicted) | 4.592 | 0.0003 | |||
SPBC1105.01 | HEAT repeat (ISS) | 3.680 | 0.0357 | |||
fio1 | Iron transport multicopper oxidase | 2.874 | 0.0112 | |||
plb1 | Phospholipase B homolog Plb1 | 2.834 | 0.0133 | |||
SPBC20F10.02c | Conserved eukaryotic protein | 2.743 | 0.0090 | |||
pho1 | Acid phosphatase activity | 2.561 | 0.0009 | |||
SPBC359.06 | Class II aldolase and adducin N-terminal domain | 2.558 | 0.0455 | |||
ght4 | Hexose transporter | 2.556 | 0.0488 | |||
ppa2 | Serine/threonine protein phosphatase (catalytic subunit) | 2.530 | 0.0142 | |||
SPAC6F12.04 | COPI coated-vesicle-associated protein (predicted) | 2.487 | 0.0039 | |||
SPBC1709.14 | Peptide N-glycanase (predicted) | 2.357 | 0.0245 | |||
SPAC26H5.09c | Oxidoreductase (predicted) | 2.267 | 0.0032 | |||
inv1 | Beta-fructofuranosidase | 2.265 | 0.0050 | |||
rst2 | Transcription factor | 2.191 | 0.0242 | |||
nnf1 | Kinetochore protein Nnf1 | 2.149 | 0.0234 | |||
hsp9 | Heat shock protein | 2.132 | 0.0212 | |||
SPAC1565.07c | TATA-binding protein-interacting protein (predicted) | 2.055 | 0.0045 | |||
SPBC887.09c | Leucine-rich repeat protein | 2.029 | 0.0002 | |||
SPAC30.03c | Translin-like protein | 2.011 | 0.0318 |
Genes with a ≥2-fold change in expression in the gcn5− mutant compared to the wild type (P ≤ 0.05). The following genes, lacking descriptive terms, also had increased expression in the gcn5− mutant: SPAC4F8.08, SPAC27D7.10c, SPAC27D7.11c, SPAC1952.04c, SPBC1861.10, SPCC1393.07c, SPCC63.15, wtf13, and wtf7.