TABLE 1.
Details of loci used in MLST scheme
| Locus | Gene product | Length of sequenced fragment (bp) | No. of alleles | No. of variable sites | % Sequence diversity [range (mean)] | dS/dN ratio | TIGR identifiera | Chromosomal location (kb) |
|---|---|---|---|---|---|---|---|---|
| adk | Adenylate kinase | 477 | 23 | 50 | 0.2-5.8 (2.5) | 23.2 | HI0349 | 376 |
| atpG | ATP synthase F1 subunit gamma | 447 | 26 | 35 | 0.2-4.2 (1.9) | 9.1 | HI0480 | 502 |
| frdB | Fumarate reductase iron-sulfur protein | 489 | 26 | 50 | 0.2-5.1 (2.6) | 119 | HI0834 | 883 |
| fucK | Fuculokinase | 345 | 22 | 32 | 0.3-5.5 (2.5) | 5.3 | HI0613 | 644 |
| mdh | Malate dehydrogenase | 405 | 36 | 50 | 0.2-6.7 (3.3) | 29.5 | HI1210 | 1,277 |
| pgi | Glucose-6-phosphate isomerase | 468 | 32 | 73 | 0.2-6.8 (4.3) | 15.7 | HI1576 | 1,645 |
| recA | RecA protein | 426 | 23 | 36 | 0.2-5.9 (2.6) | >100 | HI0600 | 622 |
a
Identifier number of the open reading frame in the genome sequence of H. influenzae strain Rd (14). TIGR, The Institute for Genomic Research.