TABLE 2.
In vitro susceptibilities of Candida spp. to fluconazole determined by BMD and Etest methods, ARTEMIS Program, 2001
| Species (no. of isolates tested) | Test Method | Cumulative % susceptible at MIC (μg/ml) ofa:
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | 64 | ||
| C. albicans (916) | BMD | 14 | 80 | 94 | 98 | 99 | 99 | 99 | 99 | 99 | 99 |
| Etest | 42 | 87 | 98 | 99 | 99 | 99 | 99 | 99 | 99 | 99 | |
| C. glabrata (235) | BMD | 0 | 0 | 0 | 1 | 6 | 25 | 57 | 89 | 93 | 95 |
| Etest | 0 | 0 | 0 | 1 | 6 | 15 | 32 | 66 | 86 | 91 | |
| C. parapsilosis (198) | BMD | 0 | 7 | 44 | 85 | 96 | 99 | 99 | 100 | ||
| Etest | 4 | 20 | 62 | 88 | 94 | 97 | 99 | 99 | 100 | ||
| C. tropicalis (150) | BMD | 0 | 5 | 25 | 57 | 93 | 99 | 99 | 99 | 99 | 100 |
| Etest | 0 | 13 | 69 | 92 | 97 | 99 | 100 | ||||
| C. krusei (43) | BMD | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14 | 56 | 98 |
| Etest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 37 | 58 | |
| C. lusitaniae (24) | BMD | 4 | 21 | 67 | 88 | 92 | 96 | 96 | 96 | 96 | 100 |
| Etest | 8 | 29 | 54 | 83 | 92 | 96 | 96 | 96 | 96 | 96 | |
a
MICs were determined according to NCCLS guidelines (19).