TABLE 1.
Antimicrobial | MIC (μg/ml)
|
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Broth microdilution
|
E test
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Case 1 | Case 2 | Case 3 | Type strain DSM 44445T | Range | Case 1 | Case 2 | Case 3 | Type strain DSM 44445T | Range | |
Ampicillin | 2 | 2 | 2 | 2 | 2 | 2 | 0.5 | 1 | 2 | 0.5-2 |
Amoxicillin-clavulanic acida | 32 | 16 | 16 | 32 | 16-32 | 16 | 16 | 16 | 8 | 8-16 |
Cefotaxime | 16 | 4 | 4 | 16 | 4-16 | >32 | >32 | >32 | >32 | >32 |
Ceftriaxone | 16 | 4 | 8 | 16 | 8-16 | >32 | >32 | >32 | >32 | >32 |
Imipenem | ≤0.5 | ≤0.5 | ≤0.5 | ≤0.5 | ≤0.5 | 0.032 | 0.064 | 0.064 | 0.016 | 0.016-0.064 |
Ciprofloxacin | 8 | 4 | 8 | 8 | 8 | >32 | >32 | >32 | >32 | >32 |
Gentamicin | 4 | 8 | 4 | 8 | 4-8 | 2 | 8 | 2 | 4 | 2-8 |
Amikacin | ≤2 | ≤2 | ≤2 | ≤2 | ≤2 | 0.25 | 0.25 | 0.125 | 0.25 | 0.125-0.25 |
Minocycline | 4 | 4 | 2 | 4 | 2-4 | 4 | 4 | 2 | 4 | 2-4 |
Trimethoprim-sulfamethoxazole | 1/19 | 0.5/9.5 | 1/19 | 0.5/9.5 | 0.5/9.5-1/19 | 0.12/2.3 | 0.25/4.75 | 0.12/2.3 | 0.064/1.1 | 0.064/1.1-0.25/4.75 |
All four isolates were positive for beta-lactamase, which was only detectable after induction with clavulanic acid, by the nitrocefin disk method.