FIG. 2.

CFA/I- and CS14-specific IgA antibody responses in the plasma of ETEC vaccine recipients. Data for the IgA antibody response in plasma in children after receiving 2 doses of the CF-BS-ETEC vaccine to CFA/I and to a cross-reacting CS14 antigen are shown. Responses are shown prior to immunization (Pre) and 7 days after intake of the first (1st) and the second vaccine dose given at an interval of 14 days (2nd). Bars are geometric means, and the lines are SEM. The responder frequency (percent) indicates the number responding per total number studied. Asterisks indicate statistically significant differences in comparisons of the preimmunization titer (Pre) to that seen 7 days after the first or second vaccine dose (*, P < 0.05; **, P = 0.001; ***, P < 0.001).