Skip to main content
. 2003 May;77(9):5209–5217. doi: 10.1128/JVI.77.9.5209-5217.2003

FIG. 5.

FIG. 5.

IgG responses in serum to MV H antigen in cotton rats and mice immunized with MV H DNA vaccine plasmids. Cotton rats were immunized i.m. on days 0, 28, and 56 with 100 μg of pGA3-mH or pMSIN-H in a volume of 100 μl. IgG responses to MV H antigen in serum were measured by ELISA and PRN assay on days 0, 28, 56, and 84. Mice were immunized in a similar way but received only two doses (on days 0 and 28). IgG responses to MV H antigen in serum were measured by ELISA and PRN assay on days 0, 28, and 56. Negative control groups included animals immunized with 100 μg of empty plasmids (pGA3 and pSINCP) or PBS. GM titers ± the SE from four to five animals are indicated. The numbers of animals that seroconverted within each group (i.e., that manifested a fourfold increase in antibody titers compared to preimmunization levels) are indicated. ✽, Significant increases (P < 0.05) in antibody titers after immunization. EU, ELISA unit(s).