TABLE 2.

Ad genomes lacking the right ITR are packaged efficiently^a

Expt	Nuclear DNA		Viral DNA		Relative ratio		Relative packaging efficiency
	% Cut	% Intact	% Cut	% Intact	Cut	Intact
1	25	75	19	81	0.8	1.1	0.7
2	11	89	13	87	1.2	1.0	1.2

^aShown are the results of determining relative quantities of cut and intact genomes from two experiments (Experiments 1 and 2). Ad(double HO) and Ad(HO gene) were coinfected, and nuclear and viral DNA was analyzed by Southern blot hybridization as shown in Fig. 4. Calculations of the relative levels of nuclear, viral, and packaged DNAs were made as described for Table 1.