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. 2003 May;77(9):5084–5097. doi: 10.1128/JVI.77.9.5084-5097.2003

FIG. 4.

FIG. 4.

FIG. 4.

Comparison of viral ORF 70 and cellular TS homologs. (A) Amino acid sequence alignment of the partial vTS sequences obtained from RFHVMm and RFHVMn with the comparable regions of other viral and cellular TS homologs. The numbering is derived from the KSHV vTS sequence. (B) Phylogenetic analysis of the alignment in A with the protein maximum-likelihood method. Bootstrap values from 100 replica samplings and the scale for substitutions per site are provided. VZV, human varicella-zoster virus (NP_040136); VZVpm, patas monkey varicella-zoster virus (NP_077428); human TS (YXHUT); mouse TS (YXMSI); yeast TS, Saccharomyces cerevisiae (P06785); insect TS, Anopheles sp. (EAA07160); plant TS, Arabidopsis thaliana (AAA32788). See Table 1 for other accession numbers.