Table 1.

Hepatic colonization following intrasplenically injected B16M cells into WT, IL-1β^−/−, or ICE^−/− mice

Mouse group	Metastasis density, no. foci per 100 mm3	Metastasis volume, % liver volume
Experiment I
WT	234.16  ±  58.36*	66.18%
IL-1β−/−	25.18  ±  21.02†	10.05%
ICE−/−	13.56  ±  16.20†	2.1%
Experiment II
WT	198.40  ±  100.54	59.62%
IL-1β−/−	33.79  ±  19.89†	9.70%
ICE−/−	27.73  ±  15.68†	8.08%

^*Means ± SD of two independent experiments performed one year apart (7–15 mice per group). 

^†P < 0.01 with respect to WT mice by ANOVA and the Scheffe F test.