TABLE 3.

Homologs of CoiA

Organisma	% Identityb	% Similarity	Functional annotationc
Streptococcus pneumoniae	100	100	Competence protein CoiA
Streptococcus mitis	89	92	Competence protein CoiA
Streptococcus gordonii	54	72	Competence protein
Streptococcus suis	50	68	Competence protein
Streptococcus agalactiae	49	66	Similar to hypothetical transcription factor
Streptococcus mutans	46	66	Putative competence protein/transcription factor
Lactococcus lactis	44	64	Competence protein CoiA
Lactococcus lactis	43	62	Transcription factor
Lactococcus lactis	42	62	Oligopeptidase PepF2
Streptococcus pyogenes	41	61	Putative transcription factor
Staphylococcus aureus	40	59	Hypothetical protein
Bacillus halodurans	37	56	Unknown conserved protein
Bacillus anthracis	34	57	Hypothetical protein
Bacillus thuringiensis	34	57	Possible competence protein
Enterococcus faecalis	34	57	Competence protein, putative
Bacillus cereus	33	54	Putative competence protein/transcription factor
Bacillus subtilis	33	49	Hypothetical protein
Lactobacillus plantarum	33	46	Competence protein
Bacillus licheniformis	31	49	Conserved protein
Pediococcus pentosaceus	30	50	Competence protein
Lactobacillus acidophilus	30	45	Competence protein
Listeria monocytogenes	29	50	Putative competence protein
Staphylococcus haemolyticus	29	45	Hypothetical protein
Listeria innocua	28	49	Putative competence protein
Lactobacillus johnsonii	27	48	Hypothetical protein
Staphylococcus saprophyticus	26	46	Putative competence protein
Enterococcus faecium	26	45	Competence CoiA-like
Lactobacillus gasseri	25	49	Competence protein

^aSpecies in the NCBI database with homology to CoiA.

^bProportion of identical residues in full-length alignment with S. pneumoniae CoiA.

^cFunctional annotations are as described in the NCBI database.