TABLE 1.
Recognized proteins of the AT-2 family
| Cluster and proteina | Organism | Database description | Size (no. of residues)b | Bacterial typec | gi |
|---|---|---|---|---|---|
| Cluster 1a | |||||
| Bce1 | Burkholderia cepacia R18194 | Autotransporter adhesin | 977 | β | 46316503 |
| Bce3 | Burkholderia cepacia R18194 | Autotransporter adhesin | 1,010 | β | 46315938 |
| Bce4 | Burkholderia cepacia R18194 | Autotransporter adhesin | 276 | β | 46322712 |
| Bma1 | Burkholderia mallei ATCC 23344 | Autotransporter adhesin | 373 | β | 53717377 |
| Rso1 | Ralstonia solanacearum | Putative hemagglutinin-related protein | 1,309 | β | 17549839 |
| Cluster 1b | |||||
| Dha1 | Desulfitobacterium hafniense | Autotransporter adhesin | 142 | Clostridia | 23115364 |
| Xca1 | Xanthomonas campestris pv. pelargonii | Unknown | 1,328 | γ | 7542317 |
| Xor1 | Xanthomonas oryzae pv. oryzae | Outer membrane protein XadA | 1,265 | γ | 9864182 |
| Cluster 1c | |||||
| Hin1 | Haemophilus influenzae R2846 | Autotransporter adhesin | 158 | γ | 42630309 |
| Rsp1 | Rhodobacter sphaeroides 2.4.1 | Large exoproteins involved in heme utilization or adhesion | 411 | α | 46192873 |
| Cluster 1d, Bfu1 | Burkholderia fungorum LB400 | Autotransporter adhesin | 3,068 | β | 48784624 |
| Cluster 2a | |||||
| Bhe1 | Bartonella henselae strain Houston-1 | Surface protein/Bartonella adhesin | 1,747 | α | 49237768 |
| Bhe2 | Bartonella henselae strain Houston-1 | Surface protein | 153 | α | 49237769 |
| Bme1 | Brucella melitensis 16M | Cell surface protein | 365 | α | 17988155 |
| Bqu1 | Bartonella quintana strain Toulouse | Surface protein/Bartonella adhesin | 1,065 | α | 49239313 |
| Bqu2 | Bartonella quintana strain Toulouse | Surface protein/Bartonella adhesin | 949 | α | 49239314 |
| Bqu3 | Bartonella quintana | VompA | 950 | α | 51949816 |
| Bqu4 | Bartonella quintana | VompC | 970 | α | 51949818 |
| Bsu1 | Brucella suis 1330 | Hypothetical protein BR1846 | 278 | α | 23502699 |
| Bvi1 | Bartonella vinsonii subsp. arupensis | BrpB | 1,760 | α | 52355211 |
| Bvi2 | Bartonella vinsonii subsp. arupensis | BrpA | 3,620 | α | 52355212 |
| Bvi3 | Bartonella vinsonii subsp. arupensis | BrpC | 1,420 | α | 52355210 |
| Mlo1 | Mesorhizobium loti MAFF303099 | Hypothetical protein mil2848 | 1,953 | α | 13472521 |
| Sme1 | Sinorhizobium meliloti 1021 | Hypothetical protein SMc01708 | 1,291 | α | 15964211 |
| Cluster 2b | |||||
| Hdu2 | Haemophilus ducreyi 35000HP | Hypothetical protein HD1920 | 296 | γ | 33152901 |
| Hdu3 | Haemophilus ducreyi | Necessary for collagen adhesion protein | 236 | γ | 45758814 |
| Cluster 2c | |||||
| Aac1 | Actinobacillus actinomycetemcomitans | Putative adhesin/invasin | 295 | γ | 19568164 |
| Eco4 | Escherichia coli | Immunoglobulin-binding protein EibF | 459 | γ | 16923467 |
| EibA | Prophage P-EibA | Immunoglobulin-binding protein EibA | 392 | dsDNA virus | 7532792 |
| EibE | Bacteriophage P-EibE | Immunoglobulin-binding protein EibE | 487 | dsDNA virus | 7523541 |
| Hdu1 | Haemophilus ducreyi 35000HP | Serum resistance protein DrsA | 257 | γ | 33151932 |
| Mca1 | Moraxella catarrhalis | Ubiquitous surface protein A2 | 686 | γ | 18568377 |
| Nme1 | Neisseria meningitidis | Putative adhesin/invasin | 405 | β | 21427129 |
| Nme3 | Neisseria meningitidis | Putative adhesin/invasin | 355 | β | 21427156 |
| Yen1 | Yersinia enterocolitica | Adhesin YadA | 454 | γ | 1955604 |
| Yps1 | Yersinia pseudotuberculosis | Adhesin YadA precursor | 434 | γ | 141104 |
| Cluster 2d, Ppr1 | Photobacterium profundum | Hypothetical protein | 288 | γ | 46917051 |
| Cluster 3a, Hso1 | Haemophilus somnus 129PT | Autotransporter adhesin | 452 | γ | 23468079 |
| Cluster 3b | |||||
| Aac2 | Actinobacillus actinomycetemcomitans | EmaA | 1,965 | γ | 33578091 |
| Apl1 | Actinobacillus pleuropneumoniae serovar 1 strain 4074 | Autotransporter adhesin | 2,600 | γ | 46143665 |
| Bce2 | Burkholderia cepacia R18194 | Autotransporter adhesin | 1,439 | β | 46313782 |
| Bfu2 | Burkholderia fungorum LB400 | Autotransporter adhesin | 770 | β | 48787852 |
| Bma2 | Burkholderia mallei ATCC 23344 | Hemagglutinin family protein | 831 | β | 53717118 |
| Dha2 | Desulfitobacterium hafniense DCB-2 | Autotransporter adhesin | 86 | Clostridia | 53684140 |
| Eco1 | Escherichia coli O157:H7 EDL933 | Putative adhesin | 1,588 | γ | 15804146 |
| Hin2 | Haemophilus influenzae | Adhesin | 1,096 | γ | 25359414 |
| Hso2 | Haemophilus somnus 2236 | Autotransporter adhesin | 2,419 | γ | 46156748 |
| Hso3 | Haemophilus somnus 2236 | Autotransporter adhesin | 2,390 | γ | 46156040 |
| Hso4 | Haemophilus somnus 129PT | Autotransporter adhesin | 611 | γ | 23467645 |
| Hso5 | Haemophilus somnus 2236 | Autotransporter adhesin | 3,391 | γ | 32030792 |
| Hso6 | Haemophilus somnus 2236 | Autotransporter adhesin | 1,550 | γ | 46156755 |
| Hso7 | Haemophilus somnus 2236 | Autotransporter adhesin | 3,674 | γ | 46156455 |
| Nme2 | Neisseria meningitidis | Adhesin | 591 | β | 15676883 |
| Nme4 | Neisseria meningitidis | NhhA outer membrane protein | 589 | β | 14578023 |
| Pmu1 | Pasteurella multocida subsp. multocida strain Pm70 | Hsf | 2,712 | γ | 15602579 |
| Pmu2 | Pasteurella multocida subsp. multocida strain Pm70 | Hsf | 1,299 | γ | 15603435 |
| Reu1 | Ralstonia eutropha JMP134 | Autotransporter adhesin | 465 | β | 53761962 |
| Sen1 | Salmonella enterica subsp. enterica serovar Typhi strain CT18 | Putative autotransporter | 1,107 | γ | 16762618 |
| Xfa1 | Xylella fastidiosa 9a5c | Surface protein | 2,059 | γ | 15838130 |
| Xfa2 | Xylella fastidiosa 9a5c | Surface protein | 1,190 | γ | 15838575 |
| Ype1 | Yersinia pestis CO92 | Putative surface protein (partial) | 658 | γ | 16121208 |
| Ype2 | Yersinia pestis KIM | Hypothetical protein y1847 | 144 | γ | 22125740 |
| Cluster 3c | |||||
| Eco3 | Escherichia coli | IHP1-like | 436 | γ | 29367636 |
| Eco5 | Escherichia coli O157:H7 EDL933 | Hypothetical protein Z0639 | 338 | γ | 15800223 |
| Mca2 | Moraxella catarrhalis | Hemagglutinin | 2,314 | γ | 22000942 |
| Cluster 3d | |||||
| Eam1 | Erwinia amylovora | Autoagglutinating adhesin | 494 | γ | 38638179 |
| Eco2 | Escherichia coli | STEC autoagglutinating adhesin | 516 | γ | 16565696 |
| Ype3 | Yersinia pestis biovar Medievalis strain 91001 | Hypothetical protein HP1206 | 364 | γ | 45441033 |
| Yps2 | Yersinia pseudotuberculosis IP 32953 | Hypothetical protein pYptb0018 | 416 | γ | 51593960 |
a
The cluster refers to the clustering pattern in the phylogenetic tree shown in Fig. 2A.
b
Size of protein is given in terms of amino acyl residues.
c
Greek letters refer to the subcategory of the proteobacteria. dsDNA, double-stranded DNA.