TABLE 4.
Residue composition of the two most conserved motifs in proteins of the AT-2 family
Motif no.a | Residue position | Amino acid residues and their frequency |
---|---|---|
1 | 18 | A29 Q13 G9 R4 S4 K3 N2 M2 T1 V1 |
19 | G46 A15 M3 N2 I1 V1 F1 | |
20 | I25 A15 V9 T7 L6 S3 M2 G1 K1 | |
21b | A64 S4 P1 | |
22 | S17 G14 A12 I11 N5 Q5 E2 M2 V1 | |
23 | A37 G12 S7 Q5 T4 M3 E1 | |
24 | L17 M15 A14 N7 I5 T4 S3 V2 G1 H1 | |
25b | A63 N2 S1 Q1 G1 V1 | |
26 | L19 M16 V14 A11 T6 I2 Q1 | |
27 | A31 S25 T8 N3 G1 L1 | |
2 | 51 | S32 Q11 T7 G7 N4 A2 K2 Y1 H1 R1 E1 |
52 | A58 G7 S4 | |
53 | V21 L21 F12 I9 Y2 M2 T1 K1 | |
54b | A61 S6 G1 P1 | |
55 | I19 V19 L16 F9 A5 S1 | |
56b | G68 V1 | |
57 | V19 Y16 A14 T5 G5 S4 I3 L1 M1 |
The positions of these two motifs in the multiple alignment can be found in Fig. 1.
The two most highly conserved residues in each motif.