FIG. 4.

Comparison of decline in anti-CMV, anti-LCV, and anti-RRV Abs in SIV-infected rhesus macaques with and without CMV disease. Anti-LCV Abs were measured in four macaques with CMV disease and two macaques without CMV disease. Anti-RRV Abs were measured in all study animals. Two macaques were RRV seronegative prior to SIV infection and were excluded from analysis. (a) Ab titers at time of death in macaques with (Yes) and without (No) CMV disease. P values were determined by Mann-Whitney U test. (b) Fold decline from pre-SIV infection values in anti-CMV, anti-LCV, and anti-RRV Abs in macaques with (Yes) and without (No) CMV disease. P values were determined by Mann-Whitney U test. (c) Relationship between decline in anti-CMV Ab and either anti-LCV Ab or anti-RRV Ab. Rho and P values were determined by the Spearman rank correlation coefficient test.