TABLE 4.

Relationship between decline in CMV-specific immunity and CMV viremia

No. of copies of plasma CMV DNA/ml	No. of time pointsa	No. (%) of time points with ≥50% decline in CMV-specific immune parameterb:
		Neutraliz- ing Ab	Total Ab	CD4+ T cells	CD8+ T cells	All 4 parametersc
<1,000	11	2 (18.2)	4 (36.4)	9 (81.8)	8 (72.7)	2 (18.2)
>1,000	7	6 (85.7)	6 (85.7)	7 (100)	7 (100)	6 (85.7)
P valued		<0.05	0.07	0.50	0.25	<0.05

^aTime points at which all four CMV-specific immune parameters were measured.

^bTime points from 10 of 11 SIV-infected macaques with detectable CMV viremia.

^cAnti-CMV neutralizing Ab, anti-CMV total Ab, CMV-specific CD4⁺ T cells and CMV-specific CD8⁺ T cells.

^dFisher's exact probability test.