Table 1.
Group (n = 5) | Dose (mg/kg) | Percent blood glucose reduction | ||||||
0.5 | 1 | 2 | 4 | 6 | 8 | 12 (hrs) | ||
Control | --- | -5.65 ± 1.80 | -8.10 ± 3.29 | -1.35 ± 6.62 | -12.09 ± 4.48 | -7.25 ± 4.90 | -4.19 ± 2.08 | -7.03 ± 8.15 |
T.chebula | 100 | -2.18 ± 3.95 | 8.45 ± 9.27 | 17.82 ± 5.38* | 20.85 ± 5.29* | 19.94 ± 6.18* | 10.98 ± 8.54 | 8.36 ± 3.18 |
T.chebula | 200 | 1.28 ± 4.72 | 20.28 ± 6.29* | 31.98 ± 8.24** | 28.45 ± 6.20** | 26.55 ± 2.70** | 18.25 ± 5.21* | 12.86 ± 8.20* |
T.chebula | 300 | -1.18 ± 4.25 | 25.88 ± 10.05** | 38.92 ± 7.18** | 42.20 ± 4.65** | 33.09 ± 8.05** | 27.85 ± 4.78** | 22.90 ± 7.55** |
Glibenclamide | 0.04 | 24.92 ± 8.20* | 32.37 ± 4.60** | 38.72 ± 10.22** | 50.44 ± 8.40** | 46.56 ± 4.60** | 23.11 ± 6.75* | 10.26 ± 11.03 |
Values are represented as mean ± SEM.; n = number of animals per group
Significant difference from control group at identical times, *P < 0.01; **P < 0.001