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. 2006 May 7;6:17. doi: 10.1186/1472-6882-6-17

Table 1.

Percent blood glucose reduction produced by T.chebula after oral administration in streptozotocin-induced diabetic rats.

Group (n = 5) Dose (mg/kg) Percent blood glucose reduction

0.5 1 2 4 6 8 12 (hrs)
Control --- -5.65 ± 1.80 -8.10 ± 3.29 -1.35 ± 6.62 -12.09 ± 4.48 -7.25 ± 4.90 -4.19 ± 2.08 -7.03 ± 8.15
T.chebula 100 -2.18 ± 3.95 8.45 ± 9.27 17.82 ± 5.38* 20.85 ± 5.29* 19.94 ± 6.18* 10.98 ± 8.54 8.36 ± 3.18
T.chebula 200 1.28 ± 4.72 20.28 ± 6.29* 31.98 ± 8.24** 28.45 ± 6.20** 26.55 ± 2.70** 18.25 ± 5.21* 12.86 ± 8.20*
T.chebula 300 -1.18 ± 4.25 25.88 ± 10.05** 38.92 ± 7.18** 42.20 ± 4.65** 33.09 ± 8.05** 27.85 ± 4.78** 22.90 ± 7.55**
Glibenclamide 0.04 24.92 ± 8.20* 32.37 ± 4.60** 38.72 ± 10.22** 50.44 ± 8.40** 46.56 ± 4.60** 23.11 ± 6.75* 10.26 ± 11.03

Values are represented as mean ± SEM.; n = number of animals per group

Significant difference from control group at identical times, *P < 0.01; **P < 0.001