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. 2000 Jan 18;97(2):767–772. doi: 10.1073/pnas.97.2.767

Figure 5.

Figure 5

Altered response to T. muris in IL-9-OVA-vaccinated mice. (A) Failure of IL-9-OVA-immunized C57BL/6 mice to expel T. muris. C57BL/6 mice immunized with IL-9-OVA complexes or vehicle (eight mice per group) were infected by oral gavage of 200 T. muris eggs. Worms were counted in ceca on day 34 after infection, and results are given as worm burden in each individual. P value between groups is 0.001. On day 13, the worm burden, assessed to verify infectivity, was similar in all animals. (B) Inhibition of T. muris-induced blood eosinophilia in IL-9-vaccinated mice. Blood eosinophils were counted 23 days after infection from infected control or IL-9-vaccinated C57BL/6 mice or uninfected naive animals. Eosinophil percentages were determined by enumerating 500 cells per slide. Results are presented as the mean percentage of blood eosinophils ± SEM (four mice per group). P value is 0.029 for the difference between OVA and IL-9-OVA groups.