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Incidence and histology of the tumors induced in three genotypes of mice subcutaneously injected with B[a]P
| Tumor | No. of tumor-bearing mice with AhR genotype
|
||
|---|---|---|---|
| +/+ | +/− | −/− | |
| Fibrosarcoma | 13 | 15 | 0 |
| Rhabdomyosarcoma | 2 | 1 | 0 |
| Squamous cell carcinoma | 2 | 1 | 0 |
| Total no. (%) | 17/17 (100%)* | 17/17 (100%)* | 0/16 (0%) |
*Significant difference in comparison with AhR(−/−) mice (P < 0.01).
