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Relative HAP sensitivity of E. coli strains mutant for suspected purine base analog-metabolizing enzymes. Mid-log-phase cells were exposed to various concentrations of HAP for 1 h at 37°C. Data were recorded as percent survival at the various HAP concentrations. Each data point represents one bacterial culture. Symbols: ○, CSH106 (wild type); •, NEB9 (moa); □, NEB10 (moa rdgB); ▪, NEB19 (moa nfi); ▵, NEB41 (moa rdgB nfi); ▴, NEB1 (rdgB).
