Table 3.

3D-BLAST search results using aminoglycoside 6′-NAT as the query

PDB code	Protein name	SCOP family name	log(E-value)	Rmsd (Å)	Sequence identitya	Species
1tiqA	Protease synthase and sporulation negative regulatory protein PaiA	N-acetyl transferase	−36.70	1.97	17	Bacillus subtilis
1qstA	GCN5 histone acetyltransferase	N-acetyl transferase	−32.70	3	14.4	Tetrahymena thermophila
1i12A	Glucosamine-phosphate NAT GNA1	N-acetyl transferase	−32.40	2.09	21.2	Saccharomyces cerevisiae
1gheA	Tabtoxin resistance protein	N-acetyl transferase	−29.70	2.36	21.5	Pseudomonas syringae
1qsoA	Histone acetyltransferase HPA2	N-acetyl transferase	−29.15	1.77	18.1	S.cerevisiae
1cm0A	Histone acetyltransferase domain of P300/CBP associating factor	N-acetyl transferase	−29.05	2.8	16.4	Homo sapiens
1ufhA	Putative acetyltransferase YycN	N-acetyl transferase	−27.52	3.39	21.6	B.subtilis
1vhsA	Putative phosphinothricin acetyltransferase YwnH	N-acetyl transferase	−26.40	2.68	18.3	B.subtilis
1n71A	Aminoglycoside 6′-NAT	N-acetyl transferase	−26.40	2.28	18.8	Enterococcus faecium
1m44A	Aminoglycoside 2′-NAT	N-acetyl transferase	−25.52	2.96	18.9	Mycobacterium tuberculosis
1mk4Ab	Hypothetical protein YqiY	N-acetyl transferase	−25.00	2.74	24.9	B.subtilis
1p0hAb	Mycothiol synthase MshD	N-acetyl transferase	−24.30	1.51	14.2	M.tuberculosis
1cjwA	Serotonin N-acetyltranferase	N-acetyl transferase	−24.22	3.04	16.6	Ovis aries
1bo4Ac	Aminoglycoside 3-NAT	N-acetyl transferase	−24.22	2.74	16.8	Serratia marcescens
1nslA	Probable acetyltransferase YdaF	N-acetyl transferase	−23.52	2.92	18.1	B.subtilis
1sqhA	Hypothetical protein cg14615-pa	Hypothetical protein cg14615-pa	−21.00	2.39	15.7	Drosophila melanogaster
1yghA	GCN5 histone acetyltransferase	N-acetyl transferase	−20.22	3.06	17.5	S.cerevisiae
1q2yA	Probable acetyltransferase YjcF	N-acetyl transferase	−19.70	2.48	19	B.subtilis
1bob	Histone acetyltransferase HAT1	N-acetyl transferase	−16.15	2.18	14.9	S.cerevisiae
1ne9A2	Peptidyltransferase FemX	FemXAB	−16.05	2.42	15.3	Weissella viridescens
1lrzA3	Methicillin resistance protein FemA	FemXAB	−16.00	2.23	14.9	Staphylococcus aureus
1iicA1	N-myristoyl transferase	N-myristoyl transferase	−16.00	2.71	16.2	S.cerevisiae
1iykA2	N-myristoyl transferase	N-myristoyl transferase	−15.00	3.04	15.3	Candida albicans
1fy7A	Histone acetyltransferase ESA1	N-acetyl transferase	−14.00	2.97	16.2	S.cerevisiae
1ro5A	Autoinducer synthesis protein LasI	Autoinducer synthetase	−13.22	3.37	19.2	Pseudomonas aeruginosa
1iicA2	N-myristoyl transferase	N-myristoyl transferase	−13.10	2.61	16.8	S.cerevisiae
1kzfA	Acyl-homoserinelactone synthase EsaI	Autoinducer synthetase	−12.70	3.74	13.7	Pantoea stewartii subsp. Stewartii
1iykA1	N-myristoyl transferase	N-myristoyl transferase	−12.30	2.85	18.6	C.albicans
1lrzA2	Methicillin resistance protein FemA	FemXAB	−11.52	3.46	16.7	S.aureus

^aSequence identity was calculated by FASTA software.

^bThese two proteins were found by PSI-BLAST if the threshold of the E-value was 0.01.

^cThe protein (bold case) is shown in Figure 5A.