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. 2000 Jan 18;97(2):793–798. doi: 10.1073/pnas.97.2.793

Table 3.

Hemodynamic effects of SERCA2a overexpression after 7 days

Treatment HR, min−1 LVSP, mm Hg +dP/dt, mm Hg/sec −dP/dt, mm Hg/sec LVEDP, mm Hg τ, msec
Failing + Ad.βgal 442  ±  27 112  ±  24 5,387  ±  818 −3,748  ±  458 12  ±  6 23  ±  2
Failing + SERCA2a 440  ±  21 147  ±  22* 7,924  ±  1,857* −6,782  ±  971* 9  ±  5 14  ±  2*

HR, heart rate; LVSP, left-ventricular systolic pressure; +dP/dt, maximal rate of rise of left-ventricular pressure; −dP/dt, maximal rate of decline of left-ventricular pressure; LVEDP, left-ventricular end-diastolic pressure; τ, time course of isovolumic relaxation; *, P < 0.05 compared to Failing + Ad.βgal.