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Serum IgG titers in groups (n = 10) of BALB/c mice immunized with either PLG/CTAB p55 gag DNA microparticles at 1 and 10 μg, PLG-CTAB DNA microparticles combined with aluminum phosphate at 1 μg, or naked DNA alone at 1 and 10 μg. Antibody titers are geometric mean titers ± SE at each time point. The responses from formulated DNA at both doses was significantly higher (P < 0.05) at all time points.
