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Serum IgG titers in groups (n = 10) of BALB/c mice immunized with either PLG/DOTAP, PLG/DDA, or PLG/CTAB p55 DNA microparticles or naked DNA alone at 1 μg dose. Antibody titers are geometric mean titers ± SE at 2 weeks post-second immunization (week 6) time point. The response from all three formulations was significantly higher (P < 0.05) than the naked DNA group.
