Table 1.
Expression of ABCG1 mRNA in human tissues compared to the expression of ABCA1 (28)
| Tissue | Relative ABCG1 mRNA expression, percent | Relative ABCA1 mRNA expression, percent |
|---|---|---|
| Adrenal gland | 126 | 99 |
| Thymus | 82 | 78 |
| Lung | 135 | 96 |
| Heart | 108 | 75 |
| Skeletal muscle | 54 | 51 |
| Brain | 66 | 44 |
| Spleen | 106 | 56 |
| Lymphnode | 54 | 52 |
| Pancreas | 26 | 29 |
| Placenta | 107 | 145 |
| Colon | 61 | 49 |
| Small intestine | 61 | 80 |
| Prostate | 47 | 48 |
| Testis | 23 | 49 |
| Ovary | 37 | 48 |
| Uterus | 32 | 63 |
| Mammary gland | 37 | 29 |
| Thyroid gland | 37 | 60 |
| Kidney | 75 | 26 |
| Liver | 100 | 100 |
| Bone marrow | 30 | 13 |
| Peripheral leukocytes | 26 | 56 |
| Fetal brain | 32 | 62 |
| Fetal liver | 34 | 123 |
| Fetal spleen | 74 | 89 |
| Fetal thymus | 50 | 70 |
| Fetal lung | 60 | 93 |
mRNA levels for individual tissues were assessed by dot blot analysis and were analyzed densitometrically. Expression values are indicated for each gene relative to its expression in the liver (100%).