Figure 5.

BLT antagonists morphologically ameliorate ischemic renal injury (hematoxylin and eosin staining). (a) Kidney obtained from sham-operated animal. (b) Ischemic kidney (iARF) obtained on postoperative day 1. Neutrophil infiltration was seen in the interstitial spaces (indicated by arrow). Brush border loss, tubular dilatation, exfoliation of tubular epithelial cells (asterisk), and denuded tubular basement membrane were evident. (c) Kidney sections from a BLT antagonist-pretreated animal.