Figure 4.

Plasma cholesterol levels in the Gulo mutant males (A) and females (B). Mean ± SEM. Homozygotes (−/−) were on chow with vitamin C supplement until 3–5 weeks before the determinations. Heterozygotes and wild-type mice were on unsupplemented chow at all times. Correlation between plasma ascorbic acid (AA) and plasma total cholesterol (C) and HDL cholesterol (D) levels in individual animals including all three genotypes. Some homozygotes were with vitamin C supplement and others were unsupplemented. ○, females; ■, males.