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. 2000 Jan 18;97(2):871–876. doi: 10.1073/pnas.97.2.871

Table 1.

Lysososomal counts

Animal No. PC S, μm2 per PC No. LY LY I LY II LY (I + II) LY lipo MVB No. LY/PC No. LY per μm2
Wt 1 11 88 35 8 13 21 14 22 3.18 0.036
Wt 2 11 91 30 6 16 22 8 12 2.73 0.03
Wt 3 11 90 38 11 13 24 14 18 3.45 0.038
Wt 4 11 93 43 26 9 35 8 23 3.9 0.042
Wt 5 11 100 44 20 13 33 11 26 4 0.04
Total 55 92.4 190 71 64 135 55 101 3.45 0.037
Atm−/− 1 11 87 68 27 27 54 16 22 6.18 0.071
Atm−/− 2 11 96 79 39 24 63 16 37 7.18 0.075
Atm−/− 3 11 95 60 29 15 44 17 24 5.45 0.057
Atm−/− 4 11 93 62 26 17 43 19 10 5.64 0.061
Atm−/− 5 11 88 63 27 22 49 14 15 5.73 0.065
Total 55 91.8 332 148* 105 253* 82* 108 6.04** 0.066

S, surface area; LY, total lysosomes; LY I, primary lysosomes; LY II, secondary lysosomes; LY lipo, lipofuschin-containing lysosomes; MVB, multivesicular bodies; Wt, wild type. *, P < 0.01; **, P < 0.001.