Table 1.
Animal | No. PC | S, μm2 per PC | No. LY | LY I | LY II | LY (I + II) | LY lipo | MVB | No. LY/PC | No. LY per μm2 |
---|---|---|---|---|---|---|---|---|---|---|
Wt 1 | 11 | 88 | 35 | 8 | 13 | 21 | 14 | 22 | 3.18 | 0.036 |
Wt 2 | 11 | 91 | 30 | 6 | 16 | 22 | 8 | 12 | 2.73 | 0.03 |
Wt 3 | 11 | 90 | 38 | 11 | 13 | 24 | 14 | 18 | 3.45 | 0.038 |
Wt 4 | 11 | 93 | 43 | 26 | 9 | 35 | 8 | 23 | 3.9 | 0.042 |
Wt 5 | 11 | 100 | 44 | 20 | 13 | 33 | 11 | 26 | 4 | 0.04 |
Total | 55 | 92.4 | 190 | 71 | 64 | 135 | 55 | 101 | 3.45 | 0.037 |
Atm−/− 1 | 11 | 87 | 68 | 27 | 27 | 54 | 16 | 22 | 6.18 | 0.071 |
Atm−/− 2 | 11 | 96 | 79 | 39 | 24 | 63 | 16 | 37 | 7.18 | 0.075 |
Atm−/− 3 | 11 | 95 | 60 | 29 | 15 | 44 | 17 | 24 | 5.45 | 0.057 |
Atm−/− 4 | 11 | 93 | 62 | 26 | 17 | 43 | 19 | 10 | 5.64 | 0.061 |
Atm−/− 5 | 11 | 88 | 63 | 27 | 22 | 49 | 14 | 15 | 5.73 | 0.065 |
Total | 55 | 91.8 | 332 | 148* | 105 | 253* | 82* | 108 | 6.04** | 0.066 |
S, surface area; LY, total lysosomes; LY I, primary lysosomes; LY II, secondary lysosomes; LY lipo, lipofuschin-containing lysosomes; MVB, multivesicular bodies; Wt, wild type. *, P < 0.01; **, P < 0.001.