Figure 4.

(A) Schematic of ‘dry’ electrophoresis box. Platinum electrodes in direct contact with the gel pass an electrical current through the matrix resulting in migration of nucleic acids towards the anode. Not to scale. Components are: 1, base; 3, lid; 13 and 17, locating pin and socket; 13a and 17a, conducting pin and socket leading to electrode in base; 9 and 10, guides locating top to base; 15 and 16, conducting pins for connecting box directly to power supply sockets in stacking frame (C); 7, support bar to which electrode in lid is threaded via holes 21, 23, 25, 27, 29, 31; 5, guillotine to the underside of which an electrode is threaded—this guillotine is lifted to admit gel and then rests directly on gel surface. (B) ‘Dry’ gel box electrophoresis 768 well MADGE gel. (C) ‘Dry’ box gel stack frames for multiple ‘dry’ box gel electrophoresis.