Figure 4.

Summary of differential couplings between Gα subunits and other receptors. The coupling specificity was assessed in PTX-pretreated neurons coexpressing Gα(C351G) and Gβ₁γ₂. The VD inhibition of N-type Ca²⁺ channels was induced by application of adenosine (10 μM), PGE₂ (1 μM), and somatostatin (0.3 μM) by using the voltage protocol described in Fig. 1. Data are presented as mean ± SEM, and numbers in parentheses indicate the number of neurons tested.