Table 4.
Antral ulcers in fasted/fed rats with oral administration of indomethacin and amide derivatives 7 and 19
Inhibitor | Dosage, mg/kg | Incidence (n = 12)* |
---|---|---|
Vehicle | 0 | 0/12 |
Indomethacin | 10 | 6/12 |
7 | 50 | 0/12 |
19 | 50 | 0/12 |
The incidence is reported as the number of rats that contained one or more major lesions (1-mm length or greater).