Table 1.
Tg founders | Tg offsprings
|
|
---|---|---|
Fraction of the offsprings | Percent of the offsprings | |
3 | 0/13 | 0 |
17 | 51/86 | 59 |
20 | 65/106 | 61 |
21 | 11/33 | 33 |
25 | 15/20 | 75 |
26 | 10/18 | 56 |
27 | 52/100 | 52 |
30 | 9/26 | 34 |
32 | 4/9 | 44 |
35 | 0/10 | 0 |
Tg founder mice were mated with wild-type C3H, and transmission frequency of the αMHC-AT1R transgene to their offsprings was determined by Southern blot analysis or PCR as described in Methods.