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Restoration of apoptosis after stable reintroduction of HIPK1 into HIPK1−/−-transformed MEFs. pcDNA3.1/Zeo plasmids containing either the control HA sequence or the full-length mouse HIPK1 cDNA were electroporated into HIPK1−/−-transformed MEFs followed by Zeocin selection. Apoptosis of transformed MEFs induced by the indicated doses of doxorubicin or γ-irradiation is shown.
