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. 2006 Jul 17;6:32. doi: 10.1186/1471-213X-6-32

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Copyright © 2006 Mauti et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Expression of plexins and neuropilins in the spinal cord at stage 18 analyzed by in situ hybridization. PlexinA1, A2, and B1 were detectable with very similar patterns in the dorsal spinal cord at stage 18, the earliest stage we investigated (arrowheads). PlexinA1 and A2 were also expressed in early motor neurons of the ventral spinal cord (open arrowheads). PlexinA2, B1 and C1 were the only plexins expressed in the floor plate (open arrow). In contrast to plexinA1 and A2, npn-1 (NP1) was expressed only in motor neurons that had migrated laterally (arrow). Npn-2 (NP2) was expressed at low levels in the dorsal spinal cord similar to plexinA1, A2, and B1 (arrowhead). Adjacent sections hybridized with the respective sense probes are shown in [Additional file 1]. Bar 50 μm.