Table 3.

Final main effects linear model of the association between baseline explanatory variables and day 7 lumefantrine concentration in ng/mL (433 patients).

Variable	Coefficient	95%CI		p-value	p-value (trend)
		lower	upper
referred from hospital OPD (vs. from outlying clinics)	-198.3	-316.9	-63.1	0.005
unsupervised treatment	-463.3	-536.8	-381.0	<0.0001
age
≥15 years	[reference]				<0.0001
5–14 years	-54.6	-233.3	158.4	0.591
<5 years	-357.9	-483.8	-208.6	<0.0001
lumefantrine dose (mg/Kg)
≥80	[reference]				0.375
65–79	-168.6	-319.3	9.1	0.062
50–64	-187.5	-348.4	5.1	0.056
<50	-36.1	-287.0	286.8	0.806
gametocytaemic at inclusion	395.2	89.5	775.7	0.009
history of dizziness at inclusion	-284.4	-414.9	-131.1	0.001
constant
			adjusted R2: 0.219
			p-value for goodness of fit: <0.0001