Table 1.
mRNA expression of Wnt ligands 1–19, Fzd receptors 1–10, Wnt antagonists sFRP1-4, WIF1, Dkk1 and Dkk4
| BM B progenitor cells | BM stromal cells (BMS) | Human fetal brain | BM B progenitor cells | BM stromal cells (BMS) | Human fetal brain | |||
| Wnt1 | +/- | - | + | Fzd1 | +/- | - | - | |
| Wnt2 | - | - | + | Fzd2 | + | - | + | |
| Wnt2B | + | + | + | Fzd3 | + | + | + | |
| Wnt3 | - | - | + | Fzd4 | + | + | + | |
| Wnt3A | +/- | - | - | Fzd5 | + | - | + | |
| Wnt4 | +/- | - | + | Fzd6 | + | + | + | |
| Wnt5A | +/- | + | + | Fzd7 | +/- | - | + | |
| Wnt5B | + | + | + | Fzd8 | ND | - | ND | |
| Wnt6 | ND | - | ND | Fzd9 | + | - | + | |
| Wnt7A | - | - | + | Fzd10 | - | - | - | |
| Wnt7B | - | - | + | Dkk1 | + | + | + | |
| Wnt8A | + | - | + | Dkk4 | + | - | - | |
| Wnt8B | ND | + | ND | sFRP1 | - | - | + | |
| Wnt9A | +/- | - | + | sFRP2 | +/- | + | + | |
| Wnt9B | +/- | + | + | sFRP3 | +/- | + | + | |
| Wnt10A | + | - | - | sFRP4 | + | - | + | |
| Wnt10B | +/- | - | + | WIF1 | + | ND | + | |
| Wnt11 | +/- | - | + | |||||
| Wnt16 | + | - | + | |||||
Genes expressed (+), not expressed (-), variably expressed between experiments(+/-), not determined (ND). N = 2. BM B progenitor cells: CD10+IgM-CD45+ cells sorted by FACS and pooled from three different donors. Total RNA from human fetal brain was used as control.