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. Author manuscript; available in PMC: 2007 Mar 1.
Published in final edited form as: Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E566–E572. doi: 10.1152/ajpendo.00427.2005

Fig. 1.

Fig. 1

Secretory profile of prolactin (PRL; A and B) and oxytocin (OT; C and D) of ovariectomized (OVX) rats ≤5 days after a single intravenous injection (black arrow) of either OT or saline. Injection of OT induced a rhythmic PRL secretion pattern of 2 surges/day (A and B, solid line) that is similar to OVX/vaginocervical stimulation [copulatory stimulus (CS)] rats (A, dashed line). By contrast, saline injection had no effect on PRL secretory profile (A and B, dotted line). Measurement of OT serum level showed high values for the first 20 h after OT injection (C, solid line; >80 pg/ml for the first 16 h). Thereafter, level fluctuations were similar to those of OVX/CS rats (C, dashed line). Injection of saline had no effect on OT secretory profile (C and D, dotted line). Values are expressed as mean ng/ml PRL ± SE (n = 3–10 serial samples) and mean pg/ml OT ± SE (n = 3–10 serial samples). *Significantly higher PRL levels for OT-injected animals compared with saline-injected animals (P < 0.05); #significantly higher PRL level for CS animals compared with saline-injected animals (P < 0.05).