Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Jul 13;103(30):11112–11117. doi: 10.1073/pnas.0601793103

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2006 by The National Academy of Sciences of the USA

PMC Copyright notice

Fig. 5. — Scheme depicting the possible DNA demethylation pathways. (A) Location of the cleavages expected for the published putative demethylation mechanisms. The curved arrows indicate the cleavages expected for the methyl excision pathway (16), the base excision pathway (26), and the dinucleotide excision pathway (25). The cleavage observed herein is indicated by the arrow labeled with an asterisk. (B) The short patch repair pathway involving a monofunctional DNA glycosylase that could generate the cleavage product observed (41). (C) The action of a bifunctional DNA glycosylase/AP lyase that could generate the cleavage product observed (41). The opening of the sugar ring that normally occurs has not been represented.