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Comparison of telomerase expression and activity and mechanistic analyses in control and anti-TER ribozyme-expressing B16 transformants
| Clone | TER expression, % | Telomerase activity, % | Melanin content, μg/5 × 106 cells | Cells in S phase, % | Apoptotic cells, % |
|---|---|---|---|---|---|
| Pooled vector | 100 | 100 | 10.8 | 38 | 0.06 |
| Pooled ribozyme | 33 | 22 | 35.3 | 23.4 | 0.3 |
| Ribozyme clone 5 | 25 | 28 | 36.4 | 21.2 | 0.5 |
