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Loss of tomosyn increases surface synaptobrevin abundance. (A) Representative images of the dorsal cord from the wild-type strain (Upper) and from the tomosyn mutant tomo-1 (Lower). (Scale bar, 5 μm.) (Ba) Absolute peak fluorescence (relative to a fluorescent bead standard, see Methods) for wild type and tomo-1. (Bb) Absolute axonal fluorescence. Data are normalized to wild type; bars are mean ± SEM. ∗∗, P < 0.001 by Student’s t test, compared with wild type.
