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Chemoreceptor oligomeric organization and insertion into Nanodiscs. (a) Diagram of a membrane-embedded chemoreceptor dimer (Left) and trimer of dimers (4) (Right) in equilibrium. (b) Diagram of a Nanodisc with two copies of a membrane scaffold protein surrounding the hydrocarbon side chains of a lipid bilayer. (c–e) Diagrams of Nanodiscs with scaffold protein MSP1D1E3(−) (13) containing one (c), three (d), or seven (e) chemoreceptor dimers.
