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Binding parameters characterizing the S100A13-metal interation
| Binding constant(μM)
|
||||
|---|---|---|---|---|
| Interaction type | Kd1 | Kd2 | ΔGb(kcal mol−1) | N (number of binding sites per monomer) |
| apo-S100A13 + Ca2+ | 8 ± 1 | 66 ± 1 | −8.065 ± 0.5 | 2 |
| apo-S100A13 + Cu2+ | 12 ± 1 | 55 ± 1 | −7.086 ± 0.5 | 2 |
| Ca2+-bound S100A13 + Cu2+ | 62 ± 1 | 120 ± 1 | −6.126 ± 0.5 | 2 |
| Cu2+-bound S100A13 + Ca2+ | 7.6 ± 1 | 140 ± 1 | −7.808 ± 0.5 | 2 |
