Table 1.

Effect of 12 wk α-tocopherol supplementation (E+) or restriction (E-) on α-tocopherol concentrations in plasma and tissue of rats^1,2,3

Tissue	E+ (100 mg all-rac-α-tocopherol)	Control (30 mg all-rac-α-tocopherol)	E- (<10 mg total tocopherol)
	n = 10	n = 13	n = 10
Plasma (μmol/L)	36 ± 6.0	20 ± 1.2	< 1.0
Liver (nmol/g protein)	2.08 ± 0.08	0.68 ± 0.04	0.007 ± 0.0005
Kidney (nmol/g protein)	1.97 ± 0.51	1.41 + 0.55	ND4
Brain (nmol/g protein)	1.90 ± 1.19	1.29 ± 0.29	0.59 ± 0.19
Testis (nmol/g protein)	1.19 ± 0.06	1.00 ± 0.06	0.026 ± 0.002

¹All 3 diets contained 460 μg phylloquinone/kg of diet

²Plasma and tissue α-tocopherol in the E+ group are higher than those in the Control and E- groups (P ≤ 0.05)

³Values are mean ± SEM

⁴Not detectable