Figure 5.

T cell recall responses to OVA immunization. Mice were immunized subcutaneously with OVA 10 weeks after BMT, and recall responses of splenic T cells were measured 14 days later. T cell proliferation in the presence of OVA was similar in recipients of T cell–depleted NOD (inverted triangles) or NOD-PI (triangles) BM and in age-matched control NOD mice (squares). Data are from individual mice pooled from three separate experiments in which BMT from NOD and NOD-PI was performed in parallel.