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. 2003 May 1;111(9):1329–1338. doi: 10.1172/JCI16750

Figure 6.

Figure 6

MOR–/– mice are more susceptible to TNBS-induced colitis. (a) Mortality rates of C57BL/6 wild-type and MOR–/– mice receiving vehicle (filled triangles and open circles, respectively) or TNBS (WT, filled diamonds; MOR–/–, filled squares) daily for 3 days after TNBS administration. (b and c) Wallace macroscopic and Ameho histologic scores of C57BL/6 wild-type and MOR–/– mice 3 days after TNBS administration. The number of mice and statistical significance are indicated and results are expressed as mean ± SEM. (d–g) Histologic examination of colon sections of wild-type and MOR–/– mice receiving vehicle (d and e) or TNBS (f and g) (×250).