Abstract
One-third of 327 newborn infants referred to the perinatal service of the Hospital for Sick Children during 1975 with suspected cardiopulmonary disorders proved to have nonstructural heart disease. Most of these were term infants with transient tachypnoea or cyanosis who recovered. A history of fetal distress or difficult delivery was commonly associated. The haemodynamic disorder for most was a delay in the normal progress of the transitional circulation. Evidence of myocardial ischaemia was present in 40%, and about half of these developed congestive heart failure. Aids to diagnosis of the ischaemic complication included echocardiography and myocardial perfusion scanning. For a small proportion specific metabolic disturbances, myocarditis, or dysrhythmia seemed the primary cause but even for these there were reasonable grounds to suspect a prenatal origin. Current general supportive measures were of value in treatment.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bucciarelli R. L., Nelson R. M., Egan E. A., Eitzman D. V., Gessner I. H. Transient tricuspid insufficiency of the newborn: a form of myocardial dysfunction in stressed newborns. Pediatrics. 1977 Mar;59(3):330–337. [PubMed] [Google Scholar]
- Campbell M. Incidence of cardiac malformations at birth and later, and neonatal mortality. Br Heart J. 1973 Feb;35(2):189–200. doi: 10.1136/hrt.35.2.189. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Goetzman B. W., Sunshine P., Johnson J. D., Wennberg R. P., Hackel A., Merten D. F., Bartoletti A. L., Silverman N. H. Neonatal hypoxia and pulmonary vasospasm: response to tolazoline. J Pediatr. 1976 Oct;89(4):617–621. doi: 10.1016/s0022-3476(76)80403-9. [DOI] [PubMed] [Google Scholar]
- Gross G. P., Hathaway W. E., McGaughey H. R. Hyperviscosity in the neonate. J Pediatr. 1973 Jun;82(6):1004–1012. doi: 10.1016/s0022-3476(73)80433-0. [DOI] [PubMed] [Google Scholar]
- KEITH J. D., ROSE V., BRAUDO M., ROWE R. D. The electrocardiogram in the respiratory distress syndrome and related cardiovascular dynamics. J Pediatr. 1961 Aug;59:167–187. doi: 10.1016/s0022-3476(61)80077-2. [DOI] [PubMed] [Google Scholar]
- Levin D. L., Heymann M. A., Kitterman J. A., Gregory G. A., Phibbs R. H., Rudolph A. M. Persistent pulmonary hypertension of the newborn infant. J Pediatr. 1976 Oct;89(4):626–630. doi: 10.1016/s0022-3476(76)80405-2. [DOI] [PubMed] [Google Scholar]
- Mitchell S. C., Korones S. B., Berendes H. W. Congenital heart disease in 56,109 births. Incidence and natural history. Circulation. 1971 Mar;43(3):323–332. doi: 10.1161/01.cir.43.3.323. [DOI] [PubMed] [Google Scholar]
- Nadas A. S., Fyler D. C., Castaneda A. R. The critically ill infant with congenital heart disease. Mod Concepts Cardiovasc Dis. 1973 Nov;42(11):53–58. [PubMed] [Google Scholar]
- Nelson R. M., Bucciarelli R. L., Eitzman D. V., Egan E. A., 2nd, Gessner I. H. Serum creatine phosphokinase MB fraction in newborns with transient tricuspid insufficiency. N Engl J Med. 1978 Jan 19;298(3):146–149. doi: 10.1056/NEJM197801192980308. [DOI] [PubMed] [Google Scholar]
- Radford D. J., Izukawa T., Rowe R. D. Congenital paroxysmal atrial tachycardia. Arch Dis Child. 1976 Aug;51(8):613–617. doi: 10.1136/adc.51.8.613. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Reid M. M., Reilly B. J., Murdock A. I., Swyer P. R. Cardiomegaly in association with neonatal hypoglycaemia. Acta Paediatr Scand. 1971 May;60(3):295–298. doi: 10.1111/j.1651-2227.1971.tb06659.x. [DOI] [PubMed] [Google Scholar]
- Rowe R. D., Hoffman T. Transient myocardial ischemia of the newborn infant: a form of severe cardiorespiratory distress in full-term infants. J Pediatr. 1972 Aug;81(2):243–250. doi: 10.1016/s0022-3476(72)80290-7. [DOI] [PubMed] [Google Scholar]
- Rowe R. D. Serious congenital heart disease in the newborn infant: diagnosis and management. Pediatr Clin North Am. 1970 Nov;17(4):967–982. doi: 10.1016/s0031-3955(16)32490-7. [DOI] [PubMed] [Google Scholar]
- Rowland T. W., Hubbell J. P., Jr, Nadas A. S. Congenital heart disease in infants of diabetic mothers. J Pediatr. 1973 Nov;83(5):815–820. doi: 10.1016/s0022-3476(73)80374-9. [DOI] [PubMed] [Google Scholar]
- Wolfe R. R., Way G. L. Cardiomyopathies in infants of diabetic mothers. Johns Hopkins Med J. 1977 Apr;140(4):177–180. [PubMed] [Google Scholar]
- deSA D. J. Myocardial changes in immature infants requiring prolonged ventilation. Arch Dis Child. 1977 Feb;52(2):138–147. doi: 10.1136/adc.52.2.138. [DOI] [PMC free article] [PubMed] [Google Scholar]